NPR's guide to the running gags from the show.
After making a huge mistake, G.O.B. acknowledges it aloud.
13 episodes feature this joke:
G.O.B. locks himself in jail; commits to Marta.
G.O.B. breaks up with Marta.
G.O.B. gets back together with Marta.
Michael finally realizes that "hermano" means "brother" in Spanish.
G.O.B. becomes CEO.
G.O.B. can't remember ever saying "I've made a huge mistake."
George Sr. escapes with the evidence.
George Sr. has an affair with Kitty.
G.O.B. messes up George Michael's campaign video.
G.O.B.'s hugest tiny mistake was having Steve Holt.
Steve Holt thinks he slept with Maeby.
G.O.B. fathered Steve Holt.
Michael realizes Rita is special.
Lucille put Michael in charge.
The Altitude Magazine story on Michael is subtitled: "Michael Bluth is Praying You'll Fix His Huge Mistake."
Related Joke: Prayer hands
The narrator thinks that Maeby made a huge mistake, but she says "Nah, I'm fine."
Sources: Joke data compiled by Adam Cole / NPR. Episode metadata from The TVDB via a Creative Commons Attribution 3.0 United States (CC BY 3.0 US) license.